Lai HY, Lee S, Toh SW, Li Y, Mateo LR, Morrion BM, Zhang Y: The clinical efficacy of a new dentifrice with zinc on plaque and gingivitis. Dentin hypersensitivity can have significant detrimental effects on your patients wellbeing and quality of life. They don't. The primary analysis population could be described as 32 participants per treatment group after lost to follow-ups of 12 out of 35 enrolled in the six-week trial who responded to the air blast stimulus for the primary outcome measure of treatment response one minute after topical application and after three days and two, four and six weeks subsequently, on SCASS with scores of2. Colgate SENSITIVE PRO-Relief has been rebranded to Colgate SENSITIVE INSTANT Relief . Desensitizing toothpastes depolarize the nerves to reduce pain signals to the brain, while occlusives block the dentin tubules to prevent painful stimuli affecting dentinal fluids. [9] stated in 2017 that arginine and strontium acetate-based desensitisers had equal clinical significance in reducing pain in DH and the other findings of the meta-analysis suggested that strontium acetate and Pro-argin should be compared for clinical efficacy immediately after topical application by independent health authorities. All authors read and approved the final manuscript. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. It remains a prevalent global disease with two different treatment modalities of home-care desensitisation with the over-the-counter (OTC) desensitisers such as potassium, This toothpaste really does not help at all with symptoms of sensitive teeth. Based on the outcomes of previous systematic reviews and meta-analysis, the rationale of the present study was to substantiate the claim of immediate pain relief after one-minute application in DH by non-invasive surface application of OTC dentifrices containing Pro-arginin Colgate Sensitive Pro-Relief, and 8% strontium acetate in Sensodyne Rapid Action and other objective was the comparative evaluation of the clinical efficacy of three technologies, BAG-based FCPS in BioMinR F, Pro-argin, and 8% strontium acetate at efficacy intervals of day three, week two, four and six for sustained inhibition of painful stimulus provoking DH as all three are dentinal tubular occluding dentifrices. The effectiveness of Colgate SENSITIVE INSTANT Relief toothpaste is built on its Pro-Argin technology with arginine and calcium from calcium carbonate. Plugging the channels that lead to sensitive tooth nerves to help relieve sensitivity. Toothpaste doesn't only clean your teeth; we have products to help with a variety of tooth issues like sensitivity and more. J Dent. The arginine, calcium carbonate and phosphate plug created by Colgate Sensitive Pro Relief remains intact with ongoing use, even when exposed to acid challenges. Frequency of dentin hypersensitivity: a cross-sectional study. [32] reported statistically significant improvement in mechanical stimulated DH with Pro-argin immediately after topical application relative to 8% strontium Acetate in 2016. Sealed channels protect against pain caused by hot, cold and sweet stimuli. Clinical efficacy of BioMin F, Colgate sensitive pro-relief and Sensodyne rapid action dentifrices in DH [Internet]. 2020;99(5):51422. Use regularly to enjoy long-lasting relief from sensitivity*. The outcomes are in concordance with the previous studies conducted by Layer and Hughes [26], Zang and Shaw [27], and Mason et al. Pessoa OF, Loretto SC, Maia LC. A meta-analysis by Matranga et al. All rights reserved. Identifier NCT 04249336. Purchased in August 2019 at Coles for $5. 2015;28(1):404. Holland GR, Narhi MN, Addy M, Gangarosa L, Orchardson R. Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. Therefore, the current study outcomes were analysed by parametric and non-parametric statistical tests after assessing the normal distribution of data and equality of variances with Shapiro Wilk statistics. 5 Hines D et al. J Clin Dent. It improves gum health and helps reduce factors that contribute to gum recession, a leading cause of tooth sensitivity. 2017;30(4):2216. Panagakos F, Schiff T, Guignon A. Dentin hypersensitivity: effective treatment with an in-office desensitizing paste containing 8% arginine and calcium carbonate. 75 ml. Colgate Sensitive Instant Relief Toothpaste starts blocking sensitivity pain instantly*. was used for statistical analysis. OTC dentifrices were applied and massaged gently with the applicator on at least two sensitive teeth per subject at two different sites, including cementoenamel junction and exposed dentinal surface, by the doctor in the office during the first visit. 0:00 / 0:30 Colgate Sensitive Pro-Relief Challenge Advert April 2012 178,990 views Mar 29, 2012 Take the Colgate Sensitive Pro-Relief Challenge to Show more 15 Dislike Share. All rights reserved. Gentle whitening formula. Colgate Sensitive Pro-Relief Instant Relief Sensitive Toothpaste - 75ml More Images Colgate Sensitive Pro-Relief Instant Relief works as a shield that blocks pathways to pain instantly. The strength of this study was that participants were randomised into four treatment groups to generalise the results for the population [32]. The Pro-Argin technology repairs sensitive areas of the teeth for instant* and long-lasting sensitivity pain relief. PubMed https://doi.org/10.17352/2394-8418.00003. Dentifrices-containing Pro-argin showed a significant reduction in DH with mean scores of (4.201.70) followed by strontium acetate (4.651.87) followed by FCPS (5.101.88) one minute after application. In contrast, there was a significant (p<0.001) reduction of 61.1% with FCPS, 60.1% with Pro-argin, 53.4% with 8% strontium acetate, and 25% with NaF-based dentifrices relative to baseline after subsequent six weeks of application observing sustained relief from DH on SCASS. With regular use, it reduces teeth sensitivity and helps to strengthen gums and prevent gum recession. 90 sold. * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. & Farooqui, W.A. Dentin hypersensitivity is characterized by a short, sharp pain arising from open dentin tubules in exposed dentin in response to external stimuli, which cannot be attributed to any other defect or disease. J Clin Periodontol. *with direct application and daily brushing. Wilcoxon Signed-Rank Test was used to compute mean scores relative to baseline at each time point. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. When it begins to interfere with oral hygiene, it can also lead to poor oral health outcomes. Providing effective solutions for this prevalent condition is a priority for every dental professional, and Colgates Pro-Argin technology is helping dentists lead the way. Yang ZY, Wang F, Lu K, Li YH, Zhou Z. Arginine-containing desensitizing toothpaste for the treatment of dentin hypersensitivity: a meta-analysis. I want to acknowledge the administrative faculty and staff assistants in the Department of Periodontology for facilitation in data collection. In our study, Pro-argin treatment revealed an immediate clinical reduction of 45.7% on SCASS, 56% on VAS used for mechanical stimuli, and 48.1% on VAS used for water jet stimuli in DH demonstrated in Tables 3, 5, and 6. Dentifrices were removed carefully after one minute of undisturbed application by rinsing the air lightly with an air syringe, and the subject was asked to spit. WAF has contributed to revising the manuscript critically and contributed to statistical analyses. Participants analyzed per group were more than thirty fulfilling the requirement of Holland's guidelines for conducting clinical trials for the management of DH [42]. Paired sample T-test was used to compute mean scores to observe change relative to baseline at each time point. Follow the directions for use. The current study outcomes showed significant decrease in pain scores of air-blasts and water jet stimulated DH with FCPS based dentifrices compared to Pro-argin and 8% strontium acetate after two, four, and six weeks subsequently, as depicted in Tables 4 and 5. Klubpris: 25,46 kr. Trials. The prime focus of treatment nowadays is based on the exploration of novel materials to remineralise the exposed tubular endings and mimic and restore the structure of the dentin [11]. For lsting relief, apply to a gentle toothbrush making sure to brush all sensitive areas of the teeth twice daily. PubMed Central Click & Collect. Colgate Sensitive Instant Relief Multiprotection Toothpaste gives you clinically proven lasting relief from sensitivity for 8 weeks when you use it twice a day. Provided by the Springer Nature SharedIt content-sharing initiative. Colgate Sensitive Pro-Relief (Toothpaste): 1.9 out of 5 stars from 91 genuine reviews on Australia's largest opinion site ProductReview.com.au. The total sample size was 140 participants, with thirty-five in each group. J Dent Probl Solut. Colgate Sensitive Pro-Relief r en tandkrm som ger omedelbar och varaktig lindring mot ilningar i tnderna. Am J Dent. This site is intended for healthcare professionals only. [41] was performed in 2017 and reported inappropriate statistical methodologies related to the normal distribution of data and equality of variances, along with lacking information in 77.1% of the thirty-five randomised trials on DH management. The Colgate Sensitive Pro Relief range features toothpastes that provide relief for sensitive teeth while addressing other common oral health concerns: Colgate Sensitive Pro Relief Repair and Prevent to protect against gingival recession. Colgate uses need to categorize. [18] in a meta-analysis in 2020. Department of Oral Biology, Dr. Ishrat-Ul-Ebad Khan Institute of Oral Health Sciences (DIKIOHS), Dow University of Health Sciences, Karachi, Pakistan, Department of Oral Biology, Dow Dental College, Dow University of Health Sciences, Karachi, Pakistan, Department of Research, School of Public Health, Dow University of Health Sciences, Karachi, Pakistan, You can also search for this author in Naturally, the researchers wondered whether it could help shield a person from acquiring the virus. Pashley D. Consensus-based recommendations for the diagnosis and management of dentin hypersensitivity. 3rd edition, Public Health England 2014. 2009; 20 (Spec Iss): 1722. For patients in the dental chair, it can be used to rapidly ease hypersensitivity pain, facilitate examinations and make dental procedures more comfortable. Colgate Sensitive Pro Relief was found to achieve 91% dentin occlusion, compared to 67% for the stannous fluoride toothpaste. A 3-day randomised clinical study investigating the efficacy of two toothpastes, designed to occlude dentine tubules, for the treatment of dentine hypersensitivity. The price for Colgate Sensitive Pro-Relief is set at RM12.80 to avoid being categorized at RM13.00. J Clin Periodontol. Compared to stannous fluoride/sodium fluoride and novamin/sodium fluoride. 4.2 5 0 221 221 Colgate Sensitive Pro-Relief Enamel Rebuild toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. For instant relief, apply directly to the sensitive tooth with finger tip, and massage gently for 1 minute, once a week or less frequently. The impact of FCPS, Pro-argin, and strontium acetate-based treatments of DH on the oral health-related quality of life together with the difference in the effectiveness of treatments were assessed individually rather than in groups in the current six-week trial. J Non Cryst Solids. da Cruz LPD, Hill RG, Chen X, Gillam DG. Plus it has the freshness you trust from Colgate! Google Scholar. In comparison, the Pro-argin can make mechanical barrier of calcium phosphate precipitates on exposed dentinal tubules up to 2m depth by the interaction of positively charged arginine, amino acids and type 1 collagen fibres [8]. 1997;24(11):80813. Another meta-analysis by Hu et al. It revealed an immediate improvement with strontium acetate more than Pro-argin on SCASS. With the exclusive Pro-Argin formula, it provides instant* and lasting** relief by plugging the channels to block tooth sensitivity. Colgate Sensitive Pro Relief Enamel Repair to strengthen weakened enamel and prevent enamel loss. Cookies policy. Last updated on May 11, 2021. https://clinicaltrials.gov/ct2/show/NCT04249336. J Dent. However, we can conclude that both Pro-argin and strontium acetate-based dentifrices disrupt the pathophysiology of DH and are effective for immediate pain relief even one minute after application on sensitive teeth. Size: 75ml (Approx.) Not all desensitizing toothpastes perform equally well. 2020;20(3):101460. To alleviate their tooth sensitivity problem, by using Colgate Sensitive Pro-Relief will give them lasting relief and they can drink ice water freely. FCPS showed the highest reduction in DH on SCASS and VAS for waterjet stimuli with mean scores of (0.970.68) (1.801.73) and Pro-Argin on VAS for mechanical stimuli with mean scores of (2.151.92) in six weeks. 2018;9(3):3306. HOW DOES Colgate SENSITIVE INSTANT Relief Repair & Prevent WORK? Therefore, the first null hypothesis was that mean scores for pain due to DH among different treatment groups for immediate relief remain. compared the Pro-Argin formulation with a calcium sodium phosphosilicate toothpaste, demonstrating 88% versus 50% occlusion respectively. Oral dentifrices have been marketed extensively for pain relief in one minute after topical application on sensitive teeth, with the claims of several dentists recommending the formulations containing Pro-argin and 8% strontium acetate. 2009;20(1):106. COLGATE. Children 6 years and younger: use a pea-sized amount for supervised tooth brushing to minimise swallowing. A systematic review. The secondary analysis population could be described as 20 participants per treatment group out of 35 enrolled in the six-week trial who responded to mechanical and water jet stimuli on VAS with scores of4 as secondary outcome measures.
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