Instayal strong is a sterile, injectable, apyrogenic, resorbable medical device made with cross-linked hyaluronic acid derived from bacterial fermentation. Instayal is in the form of a homogeneous, transparent, colourless gel contained in a pre-filled, single-use, sterile syringe with Luer-lock fitting.

Contains one sterile, single-use syringe with cross-linked hyaluronic acid gel and two 27G needles (TSK Laboratory CE 0123). Directions for use: this product is intended for administration by qualified medical personnel through injection into the dermis.

Contains one sterile, single-use syringe with cross-linked hyaluronic acid gel and two 27G needles (TSK Laboratory CE 0123). Directions for use: this product is intended for administration by qualified medical personnel through injection into the dermis.The action of Instayal consists in increasing the volume of the dermal-epidermal tissue based on the natural ability of the hydrophilic molecules of hyaluronic acid to bond with a much greater quantity of water than their weight. This fills the intradermal spaces and integrates the intercellular matrix, making the tissues firm. The cross-linking of the hyaluronic acid contained in the product makes the filling effect more stable and longer lasting.

Instayal strong must not be used: for injections in the periorbital zone (eyelids, under eye bags); for injections in blood vessels; for augmentations of the mammary tissue or for bone, tendon, ligament or muscle implants. Instayal must not be administered to patients with: previous or current autoimmune diseases or being treated with immunotherapeutic drugs; proven tendency to form hypertrophic scars or keloids or pigmentation disorders; multiple serious allergies; infections and inflammatory processes in situ or near the area being treated; coagulation disorders; recognised hypersensitivity to hyaluronic acid. Instayal must not be used by women who are pregnant, nursing or on people under the age of 18.

Instayal strong is intended for use as a temporary filler for the correction of skin defects such as wrinkles or scars. It is also recommended for pathological conditions such as lipoatrophy connected to infection from HIV and antiretroviral therapy. In particular we recommend the following use: Instayal Light for the correction of superficial lines and wrinkles, from fine to medium. Particularly indicated for defects and areas: laugh lines, barcodes, periocular wrinkles, scar sequelae (acne, chicken pox). Instayal Soft for the correction of medium-superficial wrinkles on the face. Particularly indicated for defects and areas: nasolabial wrinkles, nose, lips, frown lines. Instayal Strong for the correction of deep facial wrinkles and folds. Particularly indicated for defects and areas: nasolabial folds, marionette lines, temples, remodelling facial contours, lips. Instayal Extra Strong for the correction of very deep wrinkles on the face and to restore facial volume. Particularly indicated for defects and areas: cheekbone, malar region, sub-zygomatic region, sub-malar region, chin. Instayal Volume for the correction of wider-spread skin imperfections that affect large volumes and the body. Instayal Super Light for the correction of slight depressions and skin imperfections of the face. Particularly indicated for defects and areas: photoaging and chronoaging of the face, asphyctic and dehydrated skin.

Instayal strong is only intended to be injected subcutaneously or intradermally and must not be injected intravascularly. In performing the injection procedure, there is a potential risk that the material gets inadvertently injected into the blood vessels. In rare cases this could cause vascular occlusion, abscess, necrosis or embolic phenomena. To ensure that the needle is not inside a blood vessel during normal use of the medical device, lightly aspirate with the syringe before proceeding with the injection. Instayal was packaged to be used on one patient only and within the same session. Instayal is supplied as a single-use sterile product and must not be re-sterilised. Do not re-use. Use Instayal immediately after opening the blister pack and discard the syringe immediately after use, even if the entire contents have not been used. Do not use the product past the expiry date shown on the package or if said package is damaged, opened or stored improperly. Do not use Instayal in combination with other injectable products or mix it with other preparations before use. Do not use Instayal when the skin shows redness, swelling or changes in pigmentation; do not use Instayal with inflammation, infection or fever in progress. Patients taking medications to slow blood clotting may present with bruising or significant bleeding at the injection site. Patients taking anticoagulant medication should stop taking it, in agreement with their doctor, at least 14 days before getting Instayal injections.

Read the expiry date of the product on the adhesive label of the syringe and on the packaging. Store in a dry place, away from direct light and at a temperature between 5°C-25°C.